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A new disease profile is added to our database – Cerebellar ataxia – Holmes type. This is a rare, autosomally-inherited disease that leads to the progressive degeneration of the cerebellar cortex. Onset is generally in the fourth decade. The disease results in progressive disturbance of gait, eventual uncertainty of movements of arms, speech changes, cerebellar tremor and nystagmus are present. It is caused by genetic defect in SCA5 gene locus on 11 chromosome. Cerebellar ataxia Holmes type affects predominantly males. To receive a full description of this rare disease absolutely free of charge, please click here and send us a request. The profile was written by our consultant in neurology – Dr. Pavel Balabanov, MD.