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Petrous Bone Langerhans Cell Histiocytosis

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PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Petrous Bone Langerhans Cell Histiocytosis Treated with Radiosurgery.” (Stereotact Funct Neurosurg. 2007 Jan 12;85(2-3):129-131). Authors are Del Rio L, Lassaletta L, Martinez R, et al., from the Department of Otolaryngology, ‘La Paz’ University Hospital, Madrid, Spain. Langerhans cell histiocytosis, (LCH) is a rare disease that may show as a solitary or multifocal lesion of bone, soft tissue or viscera. Involvement of the temporal bone has been described in 15-61% of patients with LCH, usually in association with multisystemic involvement. The authors report a case of a 30-year-old man presenting with vertigo and fluctuating hearing loss caused by monosystemic LCH of the left petrous bone. The patient was treated with radiosurgery. Two years after treatment, no evidence of recurrent disease was found in the CT scan or MRI. To the authors`s knowledge, this is the first reported case of LCH of the petrous bone successfully treated with radiosurgery. To access the full abstract of the article, click here.

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