Prader-Willi syndrome

A new disease profile is added to our database – Prader-Willi syndrome. Prader-Willi syndrome (PWS) is a complex genetic disorder arising from deletion or disruption of genes in chromosome 15. Commonly associated characteristics of this disorder include diminished fetal activity, obesity, hypotonia, cognitive disabilities, problem behaviors, short stature, hypogonadotropic hypogonadism, strabismus and small hands and feet. It is estimated that one in 12 000 to 15 000 people has PWS. PWS is found in people of both sexes and all races. Most cases of PWS are attributed to a spontaneous genetic error that occurs at or near the time of conception for unknown reasons. To receive a full description of this rare disease absolutely free of charge, please click here and send us a request. The profile was written by our consultant in genetics – Dr. Dimitrina Konstantinova, PhD.