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The new issue of “Rare Diseases & Orphan Drugs” is already available on our website. The cover story of this edition focuses on the European initiatives and projects on rare diseases. Alastair Kent (Genetic Alliance UK), Antoni Montserrat (European Commission) and Domenica Taruscio (Italian National Centre for Rare Diseases) share their views and comments on these topics. You can also read about the Spring National Meeting of the medical students in Bulgaria, a short review on Parkinson diseases, as well as many interesting news on rare diseases and orphan drugs field.