Langerhans cell histiocytosis of the optic chiasm

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Langerhans cell histiocytosis of the optic chiasm.” (Clin Experiment Ophthalmol. 2007 Jan;35(1):66-8). Authors are Gangwani V, Walker M, El-Defrawy H, et al., from the Royal Eye Infirmary, Dorset County Hospital, Dorchester, UK. Langerhans cell histiocytosis (LCH) is a rare disease with clonal proliferation of dendritic histiocytes forming a pseudotumoral growth. LCH occurs most frequently in infancy or early childhood. It can present either as a localized self-limiting form or as a diffuse form with multisystem involvement. Herein an unusual case of LCH involving the optic chiasm is presented. To the authors’ knowledge, this is the first reported case of LCH presenting with visual disturbance. To access the full abstract of the article, click here.