Kikuchi disease (KD) is a benign self-limiting rare disease with unknown etiology. Prolonged fever with tender neck lymphadenitis is the most common presentation. Blood tests are not specific, and the final diagnosis is by biopsy. In this report two patients, ages seven and twelve years, who present with fever and neck lymphadenitis, are described. Both cases receive antibiotics for more than two weeks without improvement. Blood work shows high inflammatory markers. The manifestation of the second case overlaps with Hashimoto’s disease. The later diagnosis was confirmed by lymph node (LN) biopsy. Read the full article here.