Myelin oligodendrocyte glycoprotein (MOG)-associated disease (MOGAD) is a rare, antibody-mediated inflammatory demyelinating disorder of the central nervous system (CNS) that has varying phenotypes. A rare case of a nine-year-old girl who presents with a drop in her academic performance and right-sided Epilepsia partialis continua is reported. Magnetic resonance imaging (MRI) of the brain detected evidence for unilateral (left) cortical encephalitis with juxtacortical edema. An electroencephalogram revealed a hemi-generalized poly spike and wave discharges in the left hemisphere, several of which correlated with myoclonic jerks. The cerebrospinal fluid (CSF) analysis was normal. Autoimmune workup resulted in a positive serum MOG-immunoglobulin G (IgG), which confirmed the diagnosis. The child showed an excellent clinical response to intravenous methylprednisolone and intravenous immunoglobulins therapy. Read the full article here.
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